Lonidamine (AF1890)
lonidamine
CAS: 50264-69-2
Molecular Formula: C15H10Cl2N2O2
Lonidamine (AF1890) - Names and Identifiers
| Name | lonidamine |
| Synonyms | af1890 lonidamin lonidamine Lonidamine (AF1890) 1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid 1-(2,4-Dichlorobenzyl)indazole-3-carboxylic acid 1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid 1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid 1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]- |
| CAS | 50264-69-2 |
| EINECS | 256-510-0 |
| InChI | InChI=1/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21) |
| InChIKey | WDRYRZXSPDWGEB-UHFFFAOYSA-N |
Lonidamine (AF1890) - Physico-chemical Properties
| Molecular Formula | C15H10Cl2N2O2 |
| Molar Mass | 321.16 |
| Density | 1.4835 (rough estimate) |
| Melting Point | 207-209°C |
| Boling Point | 537.9±45.0 °C(Predicted) |
| Flash Point | 279.1°C |
| Solubility | Soluble in DMSO (up to 25 mg/ml). |
| Vapor Presure | 2.11E-12mmHg at 25°C |
| Appearance | solid |
| Color | White |
| pKa | 3.00±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| Refractive Index | 1.6070 (estimate) |
| Physical and Chemical Properties | Crystallization from ethanol, melting point 207 °c. Soluble in methanol or acetic acid. Acute toxicity LD50 mice, rats (mg/kg):900,1700 oral; 435,525 intraperitoneal injection. |
| Use | Broad-spectrum antineoplastic drugs can be used for the treatment of various tumors such as breast cancer, prostate cancer, lung cancer and brain tumors |
Lonidamine (AF1890) - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R60 - May impair fertility R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
| RTECS | NK7886000 |
| HS Code | 29339900 |
| Toxicity | LD50 in mice, rats (mg/kg): 900, 1700 orally; 435, 525 i.p. (Heywood) |
Supplier List
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Product Name: Lonidamine Visit Supplier Webpage Request for quotationCAS: 50264-69-2
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Spot supply
Product Name: Lonidamine Visit Supplier Webpage Request for quotationCAS: 50264-69-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Lonidamine Visit Supplier Webpage Request for quotationCAS: 50264-69-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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